E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis

Muniyappanavar N S, Jnaneshwara P Shenoy, Shivakumar J.

Abstract
Background: Idiopathic scoliosis, which accounts for the 80-85% of all lateral spine curvatures, distorts the chest wall anatomy and results in functional pulmonary disability.

Aims and Objectives: The aim of this study is to evaluate the pulmonary function in patients with asymptomatic idiopathic scoliosis and matched controls and to study the correlation between the degree of spinal deformity (Cobb’s angle) and pulmonary function test (PFT) parameters.

Materials and Methods: This study included 35 (27 males and 8 females) patients with idiopathic scoliosis in the age group of 15-30 years, with mean Cobb’s angle 62°. Standing anteroposterior X-rays of the spine were taken. The radiographs were assessed and angle of curvature was measured by the Cobb’s method. PFT parameters were recorded and compared with matched controls, and their correlation with Cobb’s angle was studied. The data were analyzed with the Student’s unpaired t-test and Pearson’s correlation coefficient.

Results: Pulmonary parameters such as tidal volume, vital capacity (VC), forced VC (FVC), forced expiratory volume in first second (FEV1), maximum mid-expiratory flow rate, peak expiratory flow rate, and maximum voluntary ventilation were significantly reduced in scoliosis patients than controls, and they were inversely correlated with Cobb’s angle. However, the mean FEV1/FVC ratio at rest in scoliosis patients was within normal limits and the ratio was not correlated with Cobb’s angle.

Conclusion: Thus, it can be concluded that patients with idiopathic scoliosis show reduced lung volumes and capacity on PFT and the pulmonary parameters show strong inverse correlation with the severity of the spinal deformity (Cobb’s angle).

Key words: Maximum Voluntary Ventilation; Peak Expiratory Flow Rate; Cobb’s Angle; Scoliosis; Pulmonary Functions


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Citation Tools
Related Records
 Articles by Muniyappanavar N S
Articles by Jnaneshwara P Shenoy
Articles by Shivakumar J
on Google
on Google Scholar
Article Statistics
 Viewed: 1031
Downloaded: 289
Cited: 0

How to Cite this Article
Pubmed Style

S MN, Shenoy JP, J S. Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. Natl J Physiol Pharm Pharmacol. 2017; 7(10): 1104-1108. doi:10.5455/njppp.2017.7.0518123052017


Web Style

S MN, Shenoy JP, J S. Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. http://www.njppp.com/?mno=267268 [Access: September 26, 2018]. doi:10.5455/njppp.2017.7.0518123052017


AMA (American Medical Association) Style

S MN, Shenoy JP, J S. Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. Natl J Physiol Pharm Pharmacol. 2017; 7(10): 1104-1108. doi:10.5455/njppp.2017.7.0518123052017



Vancouver/ICMJE Style

S MN, Shenoy JP, J S. Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. Natl J Physiol Pharm Pharmacol. (2017), [cited September 26, 2018]; 7(10): 1104-1108. doi:10.5455/njppp.2017.7.0518123052017



Harvard Style

S, M. N., Shenoy, J. P. & J, S. (2017) Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. Natl J Physiol Pharm Pharmacol, 7 (10), 1104-1108. doi:10.5455/njppp.2017.7.0518123052017



Turabian Style

S, Muniyappanavar N, Jnaneshwara P Shenoy, and Shivakumar J. 2017. Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (10), 1104-1108. doi:10.5455/njppp.2017.7.0518123052017



Chicago Style

S, Muniyappanavar N, Jnaneshwara P Shenoy, and Shivakumar J. "Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1104-1108. doi:10.5455/njppp.2017.7.0518123052017



MLA (The Modern Language Association) Style

S, Muniyappanavar N, Jnaneshwara P Shenoy, and Shivakumar J. "Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis." National Journal of Physiology, Pharmacy and Pharmacology 7.10 (2017), 1104-1108. Print. doi:10.5455/njppp.2017.7.0518123052017



APA (American Psychological Association) Style

S, M. N., Shenoy, J. P. & J, S. (2017) Correlation of Cobb’s angle with pulmonary function in idiopathic scoliosis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (10), 1104-1108. doi:10.5455/njppp.2017.7.0518123052017





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • How to write a thesis? [English]
    Swapnil s Agarwal, Preeti Yadav, Krishnadutt Chavali, Lavlesh Kumar
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 86-90
    » Abstract

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Most Cited Articles
  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 8 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 8 times [Click to see citing articles]

  • A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients
    Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar
    Natl J Physiol Pharm Pharmacol. 2015; 5(1): 33-35
    » Abstract & References » doi: 10.5455/njppp.2015.5.120720142
    Cited : 6 times [Click to see citing articles]

  • Prevalence and risk factors for eating disorders in Indian adolescent females
    Amit A Upadhyah, Rajesh Misra, Deepak N Parchwani, Pankaj B Maheria
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 153-157
    » Abstract & References » doi: 10.5455/njppp.2014.4.041220131
    Cited : 5 times [Click to see citing articles]

  • Newer anti-platelet and anti-thrombotic drugs on the horizon
    Ajai Garg, Anjana Pandey, Pranab Oza, Mridul Chaturvedi
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 105-110
    » Abstract & References » doi: 10.5455/njppp.2013.3.090420131
    Cited : 5 times [Click to see citing articles]

  • Rate pressure product predicts cardiovascular risk in type 2 diabetics with cardiac autonomic neuropathy
    Rishu Segan, Vidushi Gupta, Lily Walia, Naveen Mittal
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 43-47
    » Abstract & References » doi: 10.5455/njppp.2013.3.43-47
    Cited : 4 times [Click to see citing articles]

  • Effects of sixteen weeks exercise training on left ventricular dimensions and function in young athletes
    Sandip M Hulke, Yuganti P Vaidya, Amandeepkour R Ratta
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 152-158
    » Abstract & References » doi: 10.5455/njppp.2012.2.152-158
    Cited : 4 times [Click to see citing articles]

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138
    Cited : 4 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 4 times [Click to see citing articles]

  • Time domain measures of heart rate variability during acute mental stress in Type 2 diabetics- A case control study
    Anupama Deepak, Deepak A N, Shobha Nallulwar, Vitthal Khode
    Natl J Physiol Pharm Pharmacol. 2014; 4(1): 34-38
    » Abstract & References » doi: 10.5455/njppp.2014.4.080720131
    Cited : 4 times [Click to see citing articles]