E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city

Rahul, Nivedita Gupta, Sangeeta Vyas, Manisha Sankhla, Poonam Punjabi.

Abstract
Background: In recent years, occupational health hazards have grown as one of the major public health issues worldwide. In this context, petrol pump workers were studied who by virtue of their occupation is continuously exposed to the various chemical substances and volatile organic compounds liberated in the form of gasoline vapors in their breathing zone.

Aims and Objectives: To explore the effects of gasoline vapors on some biochemical parameters (the liver enzymes) among the petrol pump filling attendants working at various petrol pumps of Jaipur city.

Materials and Methods: This study was conducted with 80 subjects (40 petrol pump workers working for more than three years at various petrol pumps of Jaipur city as study group and 40 matched male adults working as peons and ward boys in the different departments of the institute were considered as the control group). Liver enzymes were assessed using fully automated analyzer (Beckman Coulter AU680) available at the Central Biochemistry Laboratory in S.M.S Hospital Jaipur. Mean±standard deviation values for each parameter were determined for both the study and control groups and compared using an unpaired t–test, and P < 0.05 was considered significant.

Results: Liver enzymes: serum glutamic pyruvic transaminase and serum glutamic oxaloacetic transaminase were found significantly higher among the petrol filling attendants in comparison to the control group, except serum alkaline phosphatase which was although higher in petrol filling attendants but statistically insignificant between the two groups.

Conclusions: This study observed that the petrol pump workers are at greater risk of developing biochemical alterations in the hepatic enzymes with time. However, further longitudinal studies with larger sample size and regular follow-ups are required to get better insights into the results.

Key words: Gasoline Derivatives; Occupational Exposures; Petrol Pump Workers; Liver Enzymes


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Rahul
Articles by Nivedita Gupta
Articles by Sangeeta Vyas
Articles by Manisha Sankhla
Articles by Poonam Punjabi
on Google
on Google Scholar
Article Statistics
 Viewed: 1081
Downloaded: 256
Cited: 0

How to Cite this Article
Pubmed Style

, Gupta N, Vyas S, Sankhla M, Punjabi P. Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. Natl J Physiol Pharm Pharmacol. 2017; 7(10): 1099-1103. doi:10.5455/njppp.2017.7.0516622052017


Web Style

, Gupta N, Vyas S, Sankhla M, Punjabi P. Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. http://www.njppp.com/?mno=266401 [Access: September 24, 2018]. doi:10.5455/njppp.2017.7.0516622052017


AMA (American Medical Association) Style

, Gupta N, Vyas S, Sankhla M, Punjabi P. Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. Natl J Physiol Pharm Pharmacol. 2017; 7(10): 1099-1103. doi:10.5455/njppp.2017.7.0516622052017



Vancouver/ICMJE Style

, Gupta N, Vyas S, Sankhla M, Punjabi P. Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. Natl J Physiol Pharm Pharmacol. (2017), [cited September 24, 2018]; 7(10): 1099-1103. doi:10.5455/njppp.2017.7.0516622052017



Harvard Style

, Gupta, N., Vyas, S., Sankhla, M. & Punjabi, P. (2017) Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. Natl J Physiol Pharm Pharmacol, 7 (10), 1099-1103. doi:10.5455/njppp.2017.7.0516622052017



Turabian Style

, Nivedita Gupta, Sangeeta Vyas, Manisha Sankhla, and Poonam Punjabi. 2017. Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. National Journal of Physiology, Pharmacy and Pharmacology, 7 (10), 1099-1103. doi:10.5455/njppp.2017.7.0516622052017



Chicago Style

, Nivedita Gupta, Sangeeta Vyas, Manisha Sankhla, and Poonam Punjabi. "Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1099-1103. doi:10.5455/njppp.2017.7.0516622052017



MLA (The Modern Language Association) Style

, Nivedita Gupta, Sangeeta Vyas, Manisha Sankhla, and Poonam Punjabi. "Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city." National Journal of Physiology, Pharmacy and Pharmacology 7.10 (2017), 1099-1103. Print. doi:10.5455/njppp.2017.7.0516622052017



APA (American Psychological Association) Style

, Gupta, N., Vyas, S., Sankhla, M. & Punjabi, P. (2017) Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city. National Journal of Physiology, Pharmacy and Pharmacology, 7 (10), 1099-1103. doi:10.5455/njppp.2017.7.0516622052017





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • How to write a thesis? [English]
    Swapnil s Agarwal, Preeti Yadav, Krishnadutt Chavali, Lavlesh Kumar
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 86-90
    » Abstract

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Most Cited Articles
  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 8 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 8 times [Click to see citing articles]

  • A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients
    Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar
    Natl J Physiol Pharm Pharmacol. 2015; 5(1): 33-35
    » Abstract & References » doi: 10.5455/njppp.2015.5.120720142
    Cited : 6 times [Click to see citing articles]

  • Prevalence and risk factors for eating disorders in Indian adolescent females
    Amit A Upadhyah, Rajesh Misra, Deepak N Parchwani, Pankaj B Maheria
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 153-157
    » Abstract & References » doi: 10.5455/njppp.2014.4.041220131
    Cited : 5 times [Click to see citing articles]

  • Newer anti-platelet and anti-thrombotic drugs on the horizon
    Ajai Garg, Anjana Pandey, Pranab Oza, Mridul Chaturvedi
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 105-110
    » Abstract & References » doi: 10.5455/njppp.2013.3.090420131
    Cited : 5 times [Click to see citing articles]

  • Rate pressure product predicts cardiovascular risk in type 2 diabetics with cardiac autonomic neuropathy
    Rishu Segan, Vidushi Gupta, Lily Walia, Naveen Mittal
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 43-47
    » Abstract & References » doi: 10.5455/njppp.2013.3.43-47
    Cited : 4 times [Click to see citing articles]

  • Effects of sixteen weeks exercise training on left ventricular dimensions and function in young athletes
    Sandip M Hulke, Yuganti P Vaidya, Amandeepkour R Ratta
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 152-158
    » Abstract & References » doi: 10.5455/njppp.2012.2.152-158
    Cited : 4 times [Click to see citing articles]

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138
    Cited : 4 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 4 times [Click to see citing articles]

  • Time domain measures of heart rate variability during acute mental stress in Type 2 diabetics- A case control study
    Anupama Deepak, Deepak A N, Shobha Nallulwar, Vitthal Khode
    Natl J Physiol Pharm Pharmacol. 2014; 4(1): 34-38
    » Abstract & References » doi: 10.5455/njppp.2014.4.080720131
    Cited : 4 times [Click to see citing articles]