E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital

Bhanu Prakash Kolasani, Prasanand Sasidharan, Divyashanthi CM, Pandiamunian Jayabal, Annabelle Rajaseharan.

Abstract
Background: Although alcoholism is associated with causation of multiple diseases, alcoholic liver disease (ALD) is the most common cause of mortality. Several drugs are being used in patients with ALD.

Aims and Objectives: The aim of this study is to evaluate the prescribing pattern of drugs used in patients with ALD.

Materials and Methods: A retrospective, observational study was done by analyzing the medical records of patients with ALD at a tertiary care teaching hospital for 3 months. A total of 146 case records of patients with ALD were reviewed and details such as demographics, specified drugs prescribed with their dose and dosage forms were recorded and analyzed.

Results: Overall, 1,365 drugs were prescribed for 146 patients, out of which hepatoprotective agents were the most commonly prescribed drugs (19.63%) followed by vitamins and minerals (16.63%) and antiulcer drugs (12.60%). The most commonly prescribed antimicrobial drug was cephalosporin (37.7%), diuretic was spironolactone (58.8%), intravenous (i.v.) fluid was 25% dextrose (45.3%) and for treating the complications like hepatic encephalopathy and variceal bleeding were lactulose (46.9%) and propranolol (80.7%), respectively. Chlordiazepoxide was the most common and the only drug prescribed for treating alcohol withdrawal symptoms.

Conclusion: Hepatoprotective agents along with vitamins and minerals were the most commonly prescribed drugs for patients with ALD. Corticosteroids were prescribed comparatively less in our study.

Key words: Alcoholic Liver Disease; Hepatoprotective Drugs; Corticosteroids; Spironolactone; Lactulose; Chlordiazepoxide


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Bhanu Prakash Kolasani
Articles by Prasanand Sasidharan
Articles by Divyashanthi CM
Articles by Pandiamunian Jayabal
Articles by Annabelle Rajaseharan
on Google
on Google Scholar
Article Statistics
 Viewed: 1446
Downloaded: 179
Cited: 0

How to Cite this Article
Pubmed Style

Kolasani BP, Sasidharan P, CM D, Jayabal P, Rajaseharan A. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol. 2017; 7(5): 538-544. doi:10.5455/njppp.2017.7.1233027012017


Web Style

Kolasani BP, Sasidharan P, CM D, Jayabal P, Rajaseharan A. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. http://www.njppp.com/?mno=251140 [Access: May 21, 2018]. doi:10.5455/njppp.2017.7.1233027012017


AMA (American Medical Association) Style

Kolasani BP, Sasidharan P, CM D, Jayabal P, Rajaseharan A. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol. 2017; 7(5): 538-544. doi:10.5455/njppp.2017.7.1233027012017



Vancouver/ICMJE Style

Kolasani BP, Sasidharan P, CM D, Jayabal P, Rajaseharan A. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol. (2017), [cited May 21, 2018]; 7(5): 538-544. doi:10.5455/njppp.2017.7.1233027012017



Harvard Style

Kolasani, B. P., Sasidharan, P., CM, D., Jayabal, P. & Rajaseharan, A. (2017) Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol, 7 (5), 538-544. doi:10.5455/njppp.2017.7.1233027012017



Turabian Style

Kolasani, Bhanu Prakash, Prasanand Sasidharan, Divyashanthi CM, Pandiamunian Jayabal, and Annabelle Rajaseharan. 2017. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, 7 (5), 538-544. doi:10.5455/njppp.2017.7.1233027012017



Chicago Style

Kolasani, Bhanu Prakash, Prasanand Sasidharan, Divyashanthi CM, Pandiamunian Jayabal, and Annabelle Rajaseharan. "Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 538-544. doi:10.5455/njppp.2017.7.1233027012017



MLA (The Modern Language Association) Style

Kolasani, Bhanu Prakash, Prasanand Sasidharan, Divyashanthi CM, Pandiamunian Jayabal, and Annabelle Rajaseharan. "Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital." National Journal of Physiology, Pharmacy and Pharmacology 7.5 (2017), 538-544. Print. doi:10.5455/njppp.2017.7.1233027012017



APA (American Psychological Association) Style

Kolasani, B. P., Sasidharan, P., CM, D., Jayabal, P. & Rajaseharan, A. (2017) Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, 7 (5), 538-544. doi:10.5455/njppp.2017.7.1233027012017





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • How to write a thesis? [English]
    Swapnil s Agarwal, Preeti Yadav, Krishnadutt Chavali, Lavlesh Kumar
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 86-90
    » Abstract

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Most Cited Articles
  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 8 times [Click to see citing articles]

  • A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients
    Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar
    Natl J Physiol Pharm Pharmacol. 2015; 5(1): 33-35
    » Abstract & References » doi: 10.5455/njppp.2015.5.120720142
    Cited : 6 times [Click to see citing articles]

  • Newer anti-platelet and anti-thrombotic drugs on the horizon
    Ajai Garg, Anjana Pandey, Pranab Oza, Mridul Chaturvedi
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 105-110
    » Abstract & References » doi: 10.5455/njppp.2013.3.090420131
    Cited : 5 times [Click to see citing articles]

  • Rate pressure product predicts cardiovascular risk in type 2 diabetics with cardiac autonomic neuropathy
    Rishu Segan, Vidushi Gupta, Lily Walia, Naveen Mittal
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 43-47
    » Abstract & References » doi: 10.5455/njppp.2013.3.43-47
    Cited : 4 times [Click to see citing articles]

  • Effects of sixteen weeks exercise training on left ventricular dimensions and function in young athletes
    Sandip M Hulke, Yuganti P Vaidya, Amandeepkour R Ratta
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 152-158
    » Abstract & References » doi: 10.5455/njppp.2012.2.152-158
    Cited : 4 times [Click to see citing articles]

  • Prevalence and risk factors for eating disorders in Indian adolescent females
    Amit A Upadhyah, Rajesh Misra, Deepak N Parchwani, Pankaj B Maheria
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 153-157
    » Abstract & References » doi: 10.5455/njppp.2014.4.041220131
    Cited : 4 times [Click to see citing articles]

  • Time domain measures of heart rate variability during acute mental stress in Type 2 diabetics- A case control study
    Anupama Deepak, Deepak A N, Shobha Nallulwar, Vitthal Khode
    Natl J Physiol Pharm Pharmacol. 2014; 4(1): 34-38
    » Abstract & References » doi: 10.5455/njppp.2014.4.080720131
    Cited : 4 times [Click to see citing articles]

  • Ratio of second to fourth digit as a predictor of performance in elite Indian volley ball players
    Kaninika Panda, Pralay Majumdar, Veena Umesh, HH Sudhakar
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 106-108
    » Abstract & References » doi: 10.5455/njppp.2014.4.011020132
    Cited : 4 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 4 times [Click to see citing articles]

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31
    Cited : 3 times [Click to see citing articles]