E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
31 / 08 / 2016

 


High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani.


Abstract
Background: There is compelling evidence that inflammation is an important risk factor in cardiovascular disease (CVD) and diabetes mellitus. High-sensitive C-reactive protein (hs-CRP) is a predictive marker of inflammation as well as metabolic syndrome.

Aims and Objectives: The purpose of this study was to correlate the significance of hs-CRP with cholesterol, triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein (LDL) in patients with long-term hyperglycemia and healthy control group.

Materials and Methods: This study involved 311 subjects (150 patients, 161 control group; between 40 and 65 years of age, mean age of patients and control group were 51.4 ± 9.6, 45.96 ± 3, respectively). Serum concentration of aforementioned analytes was measured among the patients and controls.

Results: The concentration of parameters among case and control group were total cholesterol (227.84 ± 28.3, 167.45 ± 21.63 mg/dl), LDL cholesterol (158.43 ± 25.65, 117.30 ± 31.27 mg/dl), HDL-C (27.67 ± 11.11, 51.74 ± 12.61 mg/dl), TG (211.34 ± 36.42, 98.13 ± 67.40 mg/dl), and hs-CRP (29.49 ± 5.90, 2.18 ± 1.10 mg/L) were measured by Cobas 6000 autoanalyzer. A statistically significant (P < 0.001) difference was found in both groups.

Conclusion: Diabetes mellitus has a profound effect on lipid metabolism and patient’s lipid profile need to be monitored and managed frequently to prevent further complication such as CVD that may arise as a result of dyslipidemia.

Key words: High Density Lipoprotein Cholesterol; Total Cholesterol; Low Density Lipoprotein Cholesterol; High-sensitive C-reactive Protein


 
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How to Cite this Article
Pubmed Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 480-483. doi:10.5455/njppp.2016.6.0615715072016


Web Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. https://www.njppp.com/?mno=232206 [Access: March 16, 2024]. doi:10.5455/njppp.2016.6.0615715072016


AMA (American Medical Association) Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 480-483. doi:10.5455/njppp.2016.6.0615715072016



Vancouver/ICMJE Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. Natl J Physiol Pharm Pharmacol. (2016), [cited March 16, 2024]; 6(5): 480-483. doi:10.5455/njppp.2016.6.0615715072016



Harvard Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani (2016) High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. Natl J Physiol Pharm Pharmacol, 6 (5), 480-483. doi:10.5455/njppp.2016.6.0615715072016



Turabian Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. 2016. High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 480-483. doi:10.5455/njppp.2016.6.0615715072016



Chicago Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. "High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 480-483. doi:10.5455/njppp.2016.6.0615715072016



MLA (The Modern Language Association) Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani. "High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia." National Journal of Physiology, Pharmacy and Pharmacology 6.5 (2016), 480-483. Print. doi:10.5455/njppp.2016.6.0615715072016



APA (American Psychological Association) Style

Yousef Rezaei Chianeh, Krishnananda Prabhu, Vinutha R. Bhat, Padmanabha Udupa, Azadeh Bagheri, Shivananda Baliga, Ravi Teja Chelikani (2016) High-sensitive C-reactive protein levels in diabetes associated with dyslipidemia. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 480-483. doi:10.5455/njppp.2016.6.0615715072016