E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
28 / 06 / 2012

 


Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma.


Abstract
Aims& Objective: To assess the relative efficiency of budesonide administered from different delivery devices to adult patients of chronic stable bronchial asthma as measured by pulmonary function test parameters.

Materials and Methods: This prospective study was undertaken to assess the relative efficiency of budesonide administered from different delivery devices to adult patients of chronic stable bronchial asthma as measured by pulmonary function test parameters. Fifty subjects where administered budesonide (1 mg) via nebulizer, budesonide (400 microgram) by metered dose inhaler, metered dose inhaler with spacer and dry powder inhaler consecutively each week for four weeks under direct supervision. Pulmonary function test was done before and one hour after administration of the drug on each visit.

Results: No significant difference in Peak expiratory flow rate (P=0.77), forced expiratory volume in one second (P=0.95), forced vital capacity (P=0.24) and forced expiratory volume in one second and forced vital capacity ratio (P=0.22) was seen after giving budesonide by different devices.

Conclusion: Budesonide delivered by different devices (nebulizer, metered dose inhaler, metered dose inhaler with spacer and dry powder inhaler) have similar effect on lung function in patients of chronic stable bronchial asthma and may be used interchangeably.

Key words: Budesonide; Comparative Study; Asthma


 
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How to Cite this Article
Pubmed Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. Natl J Physiol Pharm Pharmacol. 2012; 2(2): 99-106. doi:10.5455/njppp.2012.2.99-107


Web Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. https://www.njppp.com/?mno=22113 [Access: March 15, 2024]. doi:10.5455/njppp.2012.2.99-107


AMA (American Medical Association) Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. Natl J Physiol Pharm Pharmacol. 2012; 2(2): 99-106. doi:10.5455/njppp.2012.2.99-107



Vancouver/ICMJE Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. Natl J Physiol Pharm Pharmacol. (2012), [cited March 15, 2024]; 2(2): 99-106. doi:10.5455/njppp.2012.2.99-107



Harvard Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma (2012) Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. Natl J Physiol Pharm Pharmacol, 2 (2), 99-106. doi:10.5455/njppp.2012.2.99-107



Turabian Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. 2012. Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. National Journal of Physiology, Pharmacy and Pharmacology, 2 (2), 99-106. doi:10.5455/njppp.2012.2.99-107



Chicago Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. "Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma." National Journal of Physiology, Pharmacy and Pharmacology 2 (2012), 99-106. doi:10.5455/njppp.2012.2.99-107



MLA (The Modern Language Association) Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma. "Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma." National Journal of Physiology, Pharmacy and Pharmacology 2.2 (2012), 99-106. Print. doi:10.5455/njppp.2012.2.99-107



APA (American Psychological Association) Style

Dilshad Ali Rizvi, Mohammad Tariq Salman, Syed Esam Mahmood, Joydeep Sircar, Karim Ullah Ansari, Vinod Kumar Verma (2012) Comparative efficacy of Budesonide by different delivery devices in Bronchial Asthma. National Journal of Physiology, Pharmacy and Pharmacology, 2 (2), 99-106. doi:10.5455/njppp.2012.2.99-107