E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults

Shikha Baisakhiya, Pratibha Verma.

Abstract
Background: On the one hand, hypertension is an independent risk factor for glaucoma; on the other hand, hypertension is protective by increasing mean ocular perfusion pressure (MOPP). Reduction in ocular perfusion pressure results in decreased blood flow to the optic nerve head hence plays a role in the pathogenesis of glaucoma. Low MOPP would result from reduction in mean blood pressure (MBP) and increase in intraocular pressure (IOP).

Aim and Objective: The aim of the study was to find out the association between MBP, IOP, and MOPP in normal healthy adults.

Materials and Methods: The study included 300 healthy young individuals. The BP was recorded using Mercury Sphygmomanometer and IOP recording was done using Slit lamp mounted Goldman Applanation tonometer. MBP was calculated by the formula MBP = DBP+1/3 pulse pressure. The MOPP was calculated by formula: MOPP=MBP–IOP. The subjects were divided into five groups based on the value of MBP: Group 1: 71–80 mm of Hg, Group 2: 81–90 mm of Hg, Group 3: 91–100 mm of Hg, Group 4: 100–110 mm of Hg, and Group 5: >110 mm of Hg.

Results: IOP increased linearly with increase in MBP. (P < 0.001) MOPP was positively correlated with MBP in both males (r = 0.985, P < 0.001) and females (r = 0.986, P < 0.001). The MBP is positively correlated with IOP in both males (r = 0.615, P < 0.001) and females (r = 0.668, P < 0.001).

Conclusion: Increased MBP is a risk factor for raised IOP as well as raised MOPP. Whether raised MOPP is protective against primary open angle glaucoma or not is still question of debate and needs further evaluation.

Key words: Mean Blood Pressure; Intraocular Pressure; Mean Ocular Perfusion Pressure


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Shikha Baisakhiya
Articles by Pratibha Verma
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Baisakhiya S, Verma P. Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. Natl J Physiol Pharm Pharmacol. 2021; 11(2): 152-155. doi:10.5455/njppp.2021.11.09251202006102020


Web Style

Baisakhiya S, Verma P. Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. http://www.njppp.com/?mno=133484 [Access: March 01, 2021]. doi:10.5455/njppp.2021.11.09251202006102020


AMA (American Medical Association) Style

Baisakhiya S, Verma P. Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. Natl J Physiol Pharm Pharmacol. 2021; 11(2): 152-155. doi:10.5455/njppp.2021.11.09251202006102020



Vancouver/ICMJE Style

Baisakhiya S, Verma P. Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. Natl J Physiol Pharm Pharmacol. (2021), [cited March 01, 2021]; 11(2): 152-155. doi:10.5455/njppp.2021.11.09251202006102020



Harvard Style

Baisakhiya, S. & Verma, . P. (2021) Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. Natl J Physiol Pharm Pharmacol, 11 (2), 152-155. doi:10.5455/njppp.2021.11.09251202006102020



Turabian Style

Baisakhiya, Shikha, and Pratibha Verma. 2021. Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. National Journal of Physiology, Pharmacy and Pharmacology, 11 (2), 152-155. doi:10.5455/njppp.2021.11.09251202006102020



Chicago Style

Baisakhiya, Shikha, and Pratibha Verma. "Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults." National Journal of Physiology, Pharmacy and Pharmacology 11 (2021), 152-155. doi:10.5455/njppp.2021.11.09251202006102020



MLA (The Modern Language Association) Style

Baisakhiya, Shikha, and Pratibha Verma. "Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults." National Journal of Physiology, Pharmacy and Pharmacology 11.2 (2021), 152-155. Print. doi:10.5455/njppp.2021.11.09251202006102020



APA (American Psychological Association) Style

Baisakhiya, S. & Verma, . P. (2021) Association between intraocular pressure, mean blood pressure, and mean ocular perfusion pressure among normal healthy adults. National Journal of Physiology, Pharmacy and Pharmacology, 11 (2), 152-155. doi:10.5455/njppp.2021.11.09251202006102020