E-ISSN 2231-3206 | ISSN 2320-4672
 
2024, Vol: 14, Issue: 4
14 / 4Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Authorship Declaration

Original Research

Online Publishing Date:
25 / 09 / 2021

 


Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study

Chandralekha N, Padmaja Udaykumar, Rajesh S.


Abstract
Background: Skin tests like the intradermal test (IDT) and skin prick test can be used for drug hypersensitivity prediction. An IDT is done by injecting intradermally an allergen or drug solution of volume 0.02–0.05 ml by raising a small bleb 3 mm in diameter. The injection site is read after 15–20 min for immediate reactions. The IDT is routinely done before administration of full-dose antibiotic in the majority of the hospitals.

Aim and Objectives: The aims and objectives were to study the frequency of IDT dose hypersensitivity reactions to antibiotics and its outcome.

Materials and Methods: 0.2 ml of the antibiotic was injected intradermally before full dose of the same. The test reading was done after 15–30 min after the injection and we looked for wheal, flare reaction, and itching. The drug causing the reaction, time of reaction, description of the reaction, the organ affected, and the outcome of the reaction were noted.

Results: Two hundred and fifty-three patients were included in the study of which 32 patients had local hypersensitivity reactions to IDT dose. Redness and redness with induration were the most common reactions. The reaction to IDT dose of ciprofloxacin was the most commonly seen reaction in this study.

Conclusion: The present study showed that the hypersensitivity reaction to IDT dose before the full dose of the antibiotic was fairly common and the IDT is possibly helpful in preventing allergic reactions to full dose.

Key words: Hypersensitivity Reactions; Intradermal Test Dose; Intradermal Test


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Chandralekha N
Articles by Padmaja Udaykumar
Articles by Rajesh S
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

N C, Udaykumar P, S R. Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2021; 11(11): 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021

Web Style

N C, Udaykumar P, S R. Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. https://www.njppp.com/?mno=120368 [Access: March 14, 2024]. doi:10.5455/njppp.2021.11.09328202116092021

AMA (American Medical Association) Style

N C, Udaykumar P, S R. Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2021; 11(11): 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


Vancouver/ICMJE Style

N C, Udaykumar P, S R. Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2021), [cited March 14, 2024]; 11(11): 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


Harvard Style

N, C., Udaykumar, . P. & S, . R. (2021) Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. Natl J Physiol Pharm Pharmacol, 11 (11), 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


Turabian Style

N, Chandralekha, Padmaja Udaykumar, and Rajesh S. 2021. Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 11 (11), 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


Chicago Style

N, Chandralekha, Padmaja Udaykumar, and Rajesh S. "Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 11 (2021), 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


MLA (The Modern Language Association) Style

N, Chandralekha, Padmaja Udaykumar, and Rajesh S. "Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 11.11 (2021), 1287-1291. Print. doi:10.5455/njppp.2021.11.09328202116092021


APA (American Psychological Association) Style

N, C., Udaykumar, . P. & S, . R. (2021) Intradermal test dose hypersensitivity reactions to antibiotics in a tertiary care hospital: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 11 (11), 1287-1291. doi:10.5455/njppp.2021.11.09328202116092021


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Corrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About National Journal of Physiology, Pharmacy and Pharmacology

  National Journal of Physiology, Pharmacy and Pharmacology is a monthly peer reviewed journal.  The journal is having open access polic ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Publisher

publishernjppp@gmail.com

 

Editorial query

editornjppp1@gmail.com

MOB - 8780040272