E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index

Santosh V Chidri, G Vidya.

Abstract
Background: Pulmonary function is an independent risk factor for mortality in diabetes mellitus. Impaired pulmonary function, especially decreased alveolar gas exchange, can occur in cases with type 2 diabetes mellitus. Pulmonary function parameters such as forced expiratory volume at the first second (FEV1), forced vital capacity (FVC), FEV1/FVC, peak expiratory flow rate (PEFR), and FEF2575% have significant changes in diabetic cases than healthy individuals.

Aims and Objectives: This study was designed to evaluate the pulmonary functions in type 2 diabetic cases and its correlation with body mass index (BMI) and glycemic control.

Materials and Methods: A total of 100 type 2 diabetic cases and 100 age-and sex-matched control subjects between 31 and 60 years were recruited. A 2 ml blood was collected to estimate blood glucose levels and hemoglobin A1c (HbA1c). Spirometer was used to measure the various lung function parameters like forced vital capacity (FVC), forced expiratory volume at first second (FEV1), peak expiratory flow rate (PEFR), FEV1/FVC and FEF25-75%.

Results: The mean difference of age, height, weight, and BMI was statistically not significant (P > 0.05). The mean FEV1, FVC, PEFR, and FEF2575% were significantly lesser in type 2 diabetic cases than control subjects. The mean FVC, FEV1, FEF2575%, and PEFR were low in cases with HbA1c <7 compared to the cases with HbA1c >7. The mean differences between pulmonary function tests were statistically not significant. There was a negative correlation between FVC, FEV1, and HbA1c levels.

Conclusion: The pulmonary functions were reduced in type 2 diabetes cases. It is necessary to undergo pulmonary function testing periodically in diabetic cases. Regular respiratory workouts help to strengthen respiratory muscles and firm glycemic control can improve the pulmonary function in type 2 diabetic cases.

Key words: Type 2 Diabetes Mellitus; Forced Vital Capacity; Forced Expiratory Volume at the First Second; Peak Expiratory Flow Rate


 
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Pubmed Style

Chidri SV, Vidya G. Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. Natl J Physiol Pharm Pharmacol. 2020; 10(7): 553-556. doi:10.5455/njppp.2020.10.04100202025042020


Web Style

Chidri SV, Vidya G. Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. http://www.njppp.com/?mno=101321 [Access: October 01, 2020]. doi:10.5455/njppp.2020.10.04100202025042020


AMA (American Medical Association) Style

Chidri SV, Vidya G. Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. Natl J Physiol Pharm Pharmacol. 2020; 10(7): 553-556. doi:10.5455/njppp.2020.10.04100202025042020



Vancouver/ICMJE Style

Chidri SV, Vidya G. Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. Natl J Physiol Pharm Pharmacol. (2020), [cited October 01, 2020]; 10(7): 553-556. doi:10.5455/njppp.2020.10.04100202025042020



Harvard Style

Chidri, S. V. & Vidya, . G. (2020) Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. Natl J Physiol Pharm Pharmacol, 10 (7), 553-556. doi:10.5455/njppp.2020.10.04100202025042020



Turabian Style

Chidri, Santosh V, and G Vidya. 2020. Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. National Journal of Physiology, Pharmacy and Pharmacology, 10 (7), 553-556. doi:10.5455/njppp.2020.10.04100202025042020



Chicago Style

Chidri, Santosh V, and G Vidya. "Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index." National Journal of Physiology, Pharmacy and Pharmacology 10 (2020), 553-556. doi:10.5455/njppp.2020.10.04100202025042020



MLA (The Modern Language Association) Style

Chidri, Santosh V, and G Vidya. "Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index." National Journal of Physiology, Pharmacy and Pharmacology 10.7 (2020), 553-556. Print. doi:10.5455/njppp.2020.10.04100202025042020



APA (American Psychological Association) Style

Chidri, S. V. & Vidya, . G. (2020) Assessment of pulmonary functions in type 2 diabetes mellitus: Its correlation with glycemic control and body mass index. National Journal of Physiology, Pharmacy and Pharmacology, 10 (7), 553-556. doi:10.5455/njppp.2020.10.04100202025042020